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What Causes Hidradenitis Suppurativa?

Learn about the causes and triggers of hidradenitis suppurativa (HS).

This is a disease awareness website produced by UCB and is intended for a UK and Ireland audience.

What causes hidradenitis suppurativa?

HS is an autoinflammatory disease caused by the immune system malfunctioning. It is not contagious and cannot be passed from one person to another.

The current research doesn’t know exactly why some people develop this condition, but several factors seem to play a role, including:


If you have the symptoms of HS, you may need to advocate for yourself to get the right treatment for you. If you need support contact your healthcare professional.

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What are the triggers of hidradenitis suppurativa?

While there isn’t yet a cure for HS, knowing what triggers your symptoms can help you avoid flare-ups. Keep in mind that triggers can be different from one person to the next, and can even change over time. Work with your doctor to track your symptoms and find a way to manage HS that works best for you.


Common triggers to keep an eye on include:

  • Diet - some people with HS find it helpful to avoid certain foods, such as:

    • Brewer’s yeast (found in bread, beer and pizza dough)
    • Dairy
    • Sugar
    • Red meat
    • Fruits and vegetables from the nightshade family (tomatoes, aubergines, peppers, chilis, potatoes, etc.)
    • Gluten
  • Hormonal changes - some women with HS find their symptoms change (improve or worsen) during menstruation, pregnancy and menopause, or when using certain kinds of hormonal birth control

  • Hot and humid weather

  • Smoking

  • Stress

  • Tight-fitting clothes

If you’re keeping track of your personal triggers, try to focus on one thing at a time. Get more information on how to manage the symptoms of HS on our Flare-up and Scar Management page.

Want to learn more about hidradenitis suppurativa? Click below to access more information.

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Symptoms and Diagnosis of Hidradenitis Suppurativa

Learn about the symptoms of HS and how doctors diagnose it.

Read more
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How to Treat Hidradenitis Suppurativa

There is currently no cure for hidradenitis suppurativa but there are several treatments available to control HS and improve symptoms.

Read more
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Living with Hidradenitis Suppurativa

Receiving a diagnosis of HS can be tough, but there is support available to help you live a happy and full life.

Read more

The information provided on this website is not a substitute for professional medical care. If you have any concerns about your health or medicine, you should consult your healthcare specialist or general practitioner.

If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in the patient information leaflet. You can also report side effects directly in the UK via the Yellow Card Scheme website: https://yellowcard.mhra.gov.uk/ or via the the MHRA Yellow Card App in the Google Play or Apple App Store. In Ireland please report via the HPRA at https://www.hpra.ie/homepage/about-us/report-an-issue.

You can also report adverse events to UCB at UCBCares.UK@ucb.com or UCBCares.IE@ucb.com.

IE-DA-2400298. July 2024