What causes hidradenitis suppurativa?
HS is an autoinflammatory disease caused by the immune system malfunctioning. It is not contagious and cannot be passed from one person to another.
The current research doesn’t know exactly why some people develop this condition, but several factors seem to play a role, including:
Up to 40% of people who develop HS have a family member with the condition, which suggests that the condition may be linked to certain genes.
Unfortunately, it’s not yet clear exactly how genes are involved in the development of HS. Though having relatives with HS may increase your chances of developing it, there’s no direct link that guarantees you will also have it.
Smoking can increase your risk of developing HS. In fact, up to 90% of people with HS are either smokers or former smokers.
If you smoke, your doctor has probably told you that quitting can improve your symptoms and your overall quality of life. If you want to quit but are finding it difficult, your healthcare team can support you to find a method that works for you.
Being overweight can increase the risk of developing HS or lead to more severe symptoms. If you struggle with your weight and worry that it may be a factor in your HS, talk to your doctor about how to get to a weight that’s healthy for you. Even a small change can make a difference.
Women are three times more likely to develop HS than men and may experience a worsening of symptoms around hormonal changes such as pre-menstruation, menstruation, pregnancy and after pregnancy. Unfortunately, researchers don't yet understand why.
Several American studies have indicated that African Americans may be more likely to develop HS than white Americans, while another European study has shown that the prevalence of HS among black people is the same as among white people.
HS usually develops after puberty, but it can occur at any age after puberty.
People with autoimmune conditions, such as psoriasis and disorders of the endocrine system (hormonal system), such as polycystic ovary syndrome (PCOS), are more likely to develop HS.
If you have the symptoms of HS, you may need to advocate for yourself to get the right treatment for you. If you need support contact your healthcare professional.
What are the triggers of hidradenitis suppurativa?
While there isn’t yet a cure for HS, knowing what triggers your symptoms can help you avoid flare-ups. Keep in mind that triggers can be different from one person to the next, and can even change over time. Work with your doctor to track your symptoms and find a way to manage HS that works best for you.
Common triggers to keep an eye on include:
Diet - some people with HS find it helpful to avoid certain foods, such as:
Hormonal changes - some women with HS find their symptoms change (improve or worsen) during menstruation, pregnancy and menopause, or when using certain kinds of hormonal birth control
Hot and humid weather
Smoking
Stress
Tight-fitting clothes
If you’re keeping track of your personal triggers, try to focus on one thing at a time. Get more information on how to manage the symptoms of HS on our Flare-up and Scar Management page.
Want to learn more about hidradenitis suppurativa? Click below to access more information.
Learn about the symptoms of HS and how doctors diagnose it.
Read moreThere is currently no cure for hidradenitis suppurativa but there are several treatments available to control HS and improve symptoms.
Read moreReceiving a diagnosis of HS can be tough, but there is support available to help you live a happy and full life.
Read moreThe information provided on this website is not a substitute for professional medical care. If you have any concerns about your health or medicine, you should consult your healthcare specialist or general practitioner.
If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in the patient information leaflet. You can also report side effects directly in the UK via the Yellow Card Scheme website: https://yellowcard.mhra.gov.uk/ or via the the MHRA Yellow Card App in the Google Play or Apple App Store. In Ireland please report via the HPRA at https://www.hpra.ie/homepage/about-us/report-an-issue.
You can also report adverse events to UCB at UCBCares.UK@ucb.com or UCBCares.IE@ucb.com.