Systemic treatments are medicines that are injected or tablets that you swallow which affect your whole body or ‘system’. They are often prescribed by your dermatologist (skin doctor) if your psoriasis is severe and hasn’t responded to other treatments.
This medicine reduces your skin’s inflammation and slows the overproduction of your skin cells. You may feel sick when taking this medicine and you can not drink alcohol while on this.
Women must not get pregnant when taking methotrexate. There will be additional monitoring including blood tests.