- https:
//www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=391504 [accessed November 2023] - https:
//www.ncbi.nlm.nih.gov/pmc/articles/PMC4661156/ [accessed November 2023] - https:
//accesspediatrics.mhmedical.com/content.aspx?bookid=1303§ionid=79659020#1107524596 [accessed November 2023] - https:
//accesspediatrics.mhmedical.com/content.aspx?bookid=1303§ionid=79659020#1107524598 [accessed November 2023] - https:
//accesspediatrics.mhmedical.com/content.aspx?bookid=1303§ionid=79659020#110752460 [accessed June 2023] - https:
//www.myaware.org/myasthenia-and-pregnancy [accessed November 2023] - https:
//www.ncbi.nlm.nih.gov/books/NBK558935/ [accessed November 2023]
Transient Neonatal Myasthenia Gravis (TNMG)
What is it?
Transient Neonatal Myasthenia Gravis (TNMG) is a very rare disorder that affects babies born to mothers with Myasthenia Gravis, including those with minimal or no symptoms. There is evidence that the severity of MG in a mother doesn’t correspond to the severity of the disease in her baby. A child’s risk of developing TNMG - as well as the level of severity of the condition - has been associated with higher levels of maternal antibodies (the immune proteins that attack a person’s own body tissue).
Symptoms tend to appear within the first 24 hours of birth. TNMG is temporary, and symptoms usually go away within weeks or months after birth, with full recovery in 90% of patients by two months of age. Symptoms to look out for include a weak suck, lack of facial expression, and respiratory distress. Newborns with TNMG may also appear floppy due to muscle weakness. If your baby has TNMG, they are not at a greater risk of developing other types of MG in later life.
Symptoms of Transient Neonatal MG
If you think your child is experiencing symptoms of Transient Neonatal Myasthenia Gravis, here’s how to get a diagnosis for them.
Read more